These are not the side effects associated with opiate abuse — these are side effects that any individual who is prescribed an opiate painkiller is liable to experience. In addition to these physical side effects, many behavioral and psychological side effects can occur. However, the physical side effects are generally more prevalent when the medication is taken as prescribed by a medical professional. Out of all physical side effects, one of the most disruptive is excessively itchy skin.
What is in opiates that makes the skin itch severely, and what can be done to prevent this side effect from occurring? New data that was published in the Natural Chemical Biology journal suggests that some opioids can trigger an immune system response that affects one of the major receptor proteins on mast cell surfaces. Mast cells are an important part of the immune system, and they respond to certain inflammatory agents — like histamine — causing what appears to be an allergic reaction.
While it is still not well understood why some opiate narcotics lead to intense itching, it is known that some people have a more intense physical reaction than others.
Also, there may be a greater risk of liver damage if you drink three or more alcoholic beverages while you are taking acetaminophen. Do not drink alcoholic beverages.
If you think you or someone else may have taken an overdose of this medicine, get emergency help at once. Your doctor may also give naloxone to treat an overdose. Signs of an overdose include: extreme dizziness or weakness, slow heartbeat or breathing, seizures, trouble breathing, and cold, clammy skin.
Call your doctor right away if you notice these symptoms. This medicine may be habit-forming. If you feel that the medicine is not working as well, do not use more than your prescribed dose. Call your doctor for instructions. Using these medicine together may cause serious unwanted effects. This medicine may cause sleep-related breathing problems eg, sleep apnea, sleep-related hypoxemia. Your doctor may decrease your dose if you have sleep apnea stop breathing for short periods during sleep while using this medicine.
Dizziness, lightheadedness, or fainting may occur when you get up suddenly from a lying or sitting position. Getting up slowly may help lessen this problem. Also, lying down for a while may relieve the dizziness or lightheadedness. This medicine may make you dizzy, drowsy, or lightheaded. Do not drive or do anything else that could be dangerous until you know how this medicine affects you. Check with your doctor right away if you have pain or tenderness in the upper stomach, pale stools, dark urine, loss of appetite, nausea, unusual tiredness or weakness, or yellow eyes or skin.
These could be symptoms of a serious liver problem. Serious skin reactions eg, acute generalized exanthematous pustulosis, Stevens-Johnson syndrome, and toxic epidermal necrolysis can occur with this medicine. Check with your doctor right away if you have blistering, peeling, or loosening of the skin, chills, cough, diarrhea, itching, joint or muscle pain red irritated eyes, red skin lesions, often with a purple center, sore throat, sores, ulcers, or white spots in the mouth or on the lips, or unusual tiredness or weakness while you are using this medicine.
This medicine may cause serious allergic reactions, including anaphylaxis, which can be life-threatening and requires immediate medical attention. Call your doctor right away if you have a rash, itching, hoarseness, trouble breathing, trouble swallowing, or any swelling of your hands, face, or mouth while you are using this medicine. Using narcotics for a long time can cause severe constipation. To prevent this, your doctor may direct you to take laxatives, drink a lot of fluids, or increase the amount of fiber in your diet.
Be sure to follow the directions carefully, because continuing constipation can lead to more serious problems. If you have been using this medicine regularly for several weeks or longer, do not change your dose or suddenly stop using it without checking with your doctor. Your doctor may want you to gradually reduce the amount you are using before stopping it completely. This may help prevent worsening of your condition and reduce the possibility of withdrawal symptoms, including stomach cramps, anxiety, fever, irritability, nausea, restlessness, runny nose, sweating, tremors, or trouble with sleeping.
Using this medicine while you are pregnant may cause serious unwanted effects, including neonatal withdrawal syndrome in your newborn baby. Tell your doctor right away if you think you are pregnant or if you plan to become pregnant while using this medicine. Before you have any medical tests, tell the medical doctor in charge that you are taking this medicine.
The results of some tests may be affected by this medicine. Check with your doctor right away if you have anxiety, restlessness, a fast heartbeat, fever, sweating, muscle spasms, twitching, nausea, vomiting, diarrhea, or see or hear things that are not there. These may be symptoms of a serious condition called serotonin syndrome.
Your risk may be higher if you also take certain other medicines that affect serotonin levels in your body. Using too much of this medicine may cause infertility unable to have children.
Your doctor may also give naloxone to treat an overdose. Signs of an overdose include: extreme dizziness or weakness, slow heartbeat or breathing, seizures, trouble breathing, and cold, clammy skin.
Call your doctor right away if you notice these symptoms. This medicine may be habit-forming. If you feel that the medicine is not working as well, do not use more than your prescribed dose. Call your doctor for instructions. Using these medicine together may cause serious unwanted effects. This medicine may cause sleep-related breathing problems eg, sleep apnea, sleep-related hypoxemia. Your doctor may decrease your dose if you have sleep apnea stop breathing for short periods during sleep while using this medicine.
Dizziness, lightheadedness, or fainting may occur when you get up suddenly from a lying or sitting position. Getting up slowly may help lessen this problem. Also, lying down for a while may relieve the dizziness or lightheadedness. This medicine may make you dizzy, drowsy, or lightheaded.
Do not drive or do anything else that could be dangerous until you know how this medicine affects you. Check with your doctor right away if you have pain or tenderness in the upper stomach, pale stools, dark urine, loss of appetite, nausea, unusual tiredness or weakness, or yellow eyes or skin. These could be symptoms of a serious liver problem.
Serious skin reactions eg, acute generalized exanthematous pustulosis, Stevens-Johnson syndrome, and toxic epidermal necrolysis can occur with this medicine. Check with your doctor right away if you have blistering, peeling, or loosening of the skin, chills, cough, diarrhea, itching, joint or muscle pain red irritated eyes, red skin lesions, often with a purple center, sore throat, sores, ulcers, or white spots in the mouth or on the lips, or unusual tiredness or weakness while you are using this medicine.
The longer a person abuses the drug, the more likely they are to develop an opiate addiction and suffer the severe consequences of substance abuse. When abused, this opioid pain reliever produces a sense of euphoria and well-being because the drug directly targets areas in the brain responsible for reward and pleasure. Despite the fact that many people view Percocet as safer than other opioids, it works in the body the same way as heroin and is a highly addictive substance.
As a result, people who abuse the drug will likely become dependent on the substance and, ultimately, addicted to it. Although legitimate Percocet use may result in side effects, the risk of negative side effects and associated health consequences increases exponentially when the drug is abused. At PAX Memphis Recovery Center, we are dedicated to providing men and women with the individualized care they need to recover from addiction.
Starting with detox and continuing after the completion of treatment, our mental health and addiction specialists are there for our patients every step of the way. Call us today to get started. All of the information on this page has been reviewed and verified by a certified addiction professional.
She currently practices in the public domain in South Africa. She has an interest in medical writing and has a keen interest in evidence-based medicine.
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