When you are taking Celecoxib, it is very important that your doctors know if you are taking any other medicine. This includes prescription and non-prescription medicines as well as vitamins and herbal supplements. All information contained within the Johns Hopkins Arthritis Center website is intended for educational purposes only.
Physicians and other health care professionals are encouraged to consult other sources and confirm the information contained within this site. Consumers should never disregard medical advice or delay in seeking it because of something they may have read on this website. Your doctor will likely recommend an alternative treatment. The typical Celebrex dosage for primary dysmenorrhea period pain or menstrual cramps in adults is the same as for acute pain.
Celebrex is approved to treat JRA in children ages 2 years and older. If you miss a dose of Celebrex, take it as soon as you can. This can include setting an alarm on your phone or downloading a reminder app. A kitchen timer can work, too. Celebrex is taken on a short-term basis to relieve acute pain, such as back pain or menstrual cramps. But you may take Celebrex on a long-term basis for chronic conditions such as arthritis , if your doctor determines this is safe for you.
Celebrex should be taken at the lowest possible dose for the shortest possible time. Be sure to take Celebrex only as directed by your doctor. Celebrex can interact with several other medications. Different interactions can cause different effects. For instance, some interactions can interfere with how well a drug works. Other interactions can increase the number of side effects or make them more severe.
Below are certain medications that can interact with Celebrex. Before taking Celebrex, talk with your doctor and pharmacist. Tell them about all prescription, over-the-counter, and other drugs you take. Also tell them about any vitamins, herbs, and supplements you use. Sharing this information can help you avoid potential interactions.
If you have questions about drug interactions that may affect you, ask your doctor or pharmacist. Doing so can increase your risk of serious digestive problems. But in general, you should avoid any medications that contain the drugs listed above while using Celebrex. A boxed warning alerts doctors and patients about drug effects that may be dangerous.
Blood thinners are drugs that are used to treat or help prevent dangerous blood clots in your body. Taking Celebrex with blood thinners can raise your risk of bleeding, especially in your stomach or intestines.
A clinical study assessed the risk of serious digestive problems in people who took Celebrex with low-dose aspirin.
Over 9 months, ulcers, bleeding, or perforations in the stomach or intestines occurred in:. If you do take Celebrex with one of these drugs, be sure to see your doctor right away if you have any signs of bleeding in your stomach or intestines. Corticosteroids are drugs used to reduce inflammation swelling and damage. Taking corticosteroids with Celebrex can raise your risk of serious digestive problems.
If you need to take a corticosteroid with Celebrex, be sure to see your doctor right away if you have any symptoms of digestive problems. Celebrex can sometimes raise blood pressure.
Taking Celebrex with certain blood pressure medications can make these medications less effective at controlling your blood pressure. Examples of blood pressure medications that could be made less effective when taken with Celebrex include:. If you need to use blood pressure medication with Celebrex, your doctor will regularly check your blood pressure.
Taking Celebrex with diuretics, ACE inhibitors, or angiotensin II blockers can also raise your risk of kidney problems. If you need to take one of these drugs with Celebrex, you should be sure to drink plenty of fluids.
Also, your doctor will do various tests to monitor your kidneys. Taking Celebrex with certain antidepressants can raise your risk of bleeding, especially in your stomach or intestines. Taking Celebrex with digoxin can increase the level of digoxin in your body. This can increase your risk of digoxin side effects. If you need to take digoxin with Celebrex, your doctor will monitor your digoxin level. Taking Celebrex with lithium can increase the level of lithium in your body.
This can increase your risk of lithium side effects. If you need to take lithium with Celebrex, your doctor will monitor your lithium level. Taking Celebrex with methotrexate can increase your risk of methotrexate side effects. If you need to take methotrexate with Celebrex, be sure to tell your doctor if any side effects become more severe or if you develop new ones.
Your doctor will monitor you closely and adjust your treatment if needed. The drug is also used to treat RA and psoriasis. Taking Celebrex with cyclosporine can increase your risk of kidney problems. If you need to take cyclosporine with Celebrex, your doctor will monitor your kidney function and adjust your treatment as needed. Taking Celebrex with pemetrexed can increase your risk of pemetrexed side effects.
If you need to take pemetrexed with Celebrex, be sure to tell your doctor if any side effects become more severe or if you develop new ones. Fluconazole Diflucan is an antifungal drug. Taking Celebrex with fluconazole can reduce the breakdown of Celebrex in your body. This could increase the level of Celebrex and raise your risk of Celebrex side effects. Rifampin Rifadin is an antibiotic drug. Taking Celebrex with rifampin could increase the breakdown of Celebrex in your body.
This could lower the level of Celebrex and make it less effective. However, you should still check with your doctor or pharmacist before using any of these products while taking Celebrex. If you have any questions about eating certain foods with Celebrex, talk with your doctor. However, drinking alcohol with Celebrex could raise your risk of certain side effects, such as nausea, indigestion upset stomach , headache , and dizziness. Keep in mind that taking Celebrex can increase your risk of ulcers slow healing sores and bleeding in your stomach and intestines.
If you drink alcohol, talk with your doctor about how much is safe for you to drink while you take Celebrex. Other drugs are available that can treat your condition. Some may be a better fit for you than others. They can tell you about other medications that may work well for you. Note: Some of the drugs listed here are used off-label to treat these specific conditions. Examples of other drugs that may be used to treat osteoarthritis include:.
Examples of other drugs that may be used to treat rheumatoid arthritis include:. Examples of other drugs that may be used to treat juvenile rheumatoid arthritis include:. Examples of other drugs that may be used to treat ankylosing spondylitis include:. Examples of other drugs that may be used to treat primary dysmenorrhea menstrual cramps include:. Not according to the manufacturer of Celebrex, but in practice, this can be a slightly gray area. Celebrex contains a sulfonamide medication.
However, some research suggests that not every medication that contains a sulfonamide will trigger an allergic reaction in people with a sulfa allergy. So in some cases, your doctor might consider prescribing Celebrex. But the decision would be made on a case-by-case basis.
Blood thinners are drugs that are used to help prevent blood clots. NSAIDs are used to treat pain and inflammation swelling and damage. To relieve pain, you should take Celebrex at the lowest possible dose for the shortest possible time. For example, to treat acute short-term pain, like menstrual cramps , back pain , or pain following surgery, you may need to take Celebrex only for a few days or weeks. However, if you have a chronic long-term condition like arthritis , you might need to take Celebrex on a long-term basis.
You should do this only if your doctor considers it safe for you to do so. Taking Celebrex for long periods of time can raise the risk for serious side effects.
These include heart attack , stroke , and ulcers , or bleeding in your stomach or intestines. If you do take Celebrex for a long period of time, your doctor will also typically prescribe a medication to help protect your digestive system. For example, tell your doctor if you still have pain after taking mg of Celebrex a day for 2 weeks. And if you have ankylosing spondylitis , tell your doctor if you still have pain after taking mg of Celebrex a day for 6 weeks.
Your doctor may recommend increasing your dosage or suggest a different treatment. In some cases it can be safe. These can include codeine, dihydrocodeine, hydrocodone , and oxycodone Percocet. These include ulcers and bleeding in your stomach and intestines. If you need to take another pain reliever while taking Celebrex, talk with your doctor first. They can suggest the most appropriate way to manage your pain.
No, Celebrex has never been taken off the market. Two similar pain relievers, called rofecoxib Vioxx and valdecoxib Bextra , were withdrawn from the market in and And the FDA considered the risks of these drugs to outweigh their benefits. A class of drugs is a group of medications that act in a similar way. So after Vioxx and Bextra were withdrawn from the market, a large clinical study was carried out to check the safety of Celebrex.
Researchers found that the risks of heart attack and stroke with Celebrex were much lower than with Vioxx or Bextra. The study also found that the risks were lower with Celebrex than with high doses of naproxen or ibuprofen. Over a month period, 2. This was compared with 2. Based on these results, the FDA decided that benefits of Celebrex outweigh its risks. It reduces inflammation and relieves pain for various conditions. Celebrex is used to treat certain forms of arthritis as well as acute pain, including menstrual cramps.
If you have damage to tissues in your body, such as following an injury or surgery, or due to arthritis, your body makes prostaglandins. These are hormones created by an enzyme called cyclooxygenase COX. Prostaglandins are made as part of the healing process, but they also cause inflammation and pain. Prostaglandins are also responsible for causing your uterus to contract during your menstrual period. Using alcohol or tobacco with certain medicines may also cause interactions to occur.
Discuss with your healthcare professional the use of your medicine with food, alcohol, or tobacco. The presence of other medical problems may affect the use of this medicine. Make sure you tell your doctor if you have any other medical problems, especially:.
For safe and effective use of this medicine, do not take more of it, do not take it more often, and do not take it for a longer time than your doctor ordered. Taking too much of this medicine may increase the chance of unwanted effects. This medicine should come with a Medication Guide.
It is very important that you read and understand this information. Be sure to ask your doctor about anything you do not understand. If you cannot swallow the capsule, you may open it and pour the medicine to a teaspoon of cool or room temperature applesauce. This mixture must be swallowed right away without chewing and followed with a glass of water to make sure all of the mixture is swallowed.
The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so. The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.
If you miss a dose of this medicine, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not double doses. Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing. Celecoxib capsule that has been mixed with applesauce may be stored in a refrigerator and used within 6 hours.
Do not store the oral liquid bottle and reuse the remaining medicine. Throw away the bottle with the unused medicine. It is very important that your doctor check the progress of you or your child at regular visits. This will allow your doctor to see if the medicine is working properly and to decide if you should continue to take it.
Medical professionals can help you determine if long-term use of Celebrex is right for you. To avoid side effects from Celebrex, take the dose that your doctor recommended for you. Skipping doses or taking extra doses because you have a lot of pain can cause side effects, and overdosing is potentially life-threatening. If you think you may have overdosed on Celebrex, you should call the Poison Control Center at and seek medical attention as soon as possible symptoms of overdose include nausea, severe stomach pain, lethargy, tiredness, and vomit that looks like coffee grounds.
Celebrex should be stored at room temperature away from direct sunlight, moisture, and heat. Improperly stored or expired Celebrex can change chemically, affecting how the medication works and causing side effects if ingested.
Check the medication guide for more safety drug information. The good news is that other treatment options can reduce pain and inflammation.
Here are some of the most common alternatives to Celebrex:. Abruptly stopping medication can cause side effects to worsen and even result in new side effects. Skip to main content Search for a topic or drug. What is Celebrex, and what is it used for? Torres, Pharm. Top Reads in Drug Info. Can you mix Trintellix and alcohol? Does hydroxyzine for anxiety work? Do coffee and Zoloft mix?
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